abstract：OBJECTIVES:There is a paucity of evidence on bipolar I acute symptoms' presentation in the elderly individuals compared to younger patients. The current literature provides little, and at times conflicting, information on age-related bipolar disorder (BD) symptom presentation. This article aims to compare symptom profi...

journal_title：Journal of geriatric psychiatry and neurology

authors： Al Jurdi RK,Nguyen QX,Petersen NJ,Pilgrim P,Gyulai L,Sajatovic M

更新日期：2012-03-01 00:00:00

abstract：UNLABELLED:This study examined the prevalence of irritability and social isolation in veterans with dementia, with and without depression. Participants were diagnosed with dementia and enrolled in a dementia care-coordination and support-service intervention. Participants were interviewed and underwent assessment with ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Shub D,Bass DM,Morgan RO,Judge KS,Snow AL,Wilson NL,Walder A,Murry B,Kunik ME

更新日期：2011-12-01 00:00:00

abstract：:Depression predicts fall risk among older adults, and this relationship may be partially explained by depression-associated executive dysfunction, relevant to navigating demanding environments. This pilot study examined timed stepping accuracy under simple and complex dual-task conditions, using an instrumented walkwa...

journal_title：Journal of geriatric psychiatry and neurology

authors： Wright SL,Kay RE,Avery ET,Giordani B,Alexander NB

更新日期：2011-09-01 00:00:00

abstract：:Depression with mild cognitive impairment (MCI) may be associated with a high risk of dementia. Likewise, anemia and subcortical ischemic changes might be associated with depression in the elderly individuals. We examined the relationship between anemia, subcortical ischemic changes, and depressive symptoms in 388 eld...

journal_title：Journal of geriatric psychiatry and neurology

authors： Son SJ,Lee KS,Na DL,Seo SW,Kim CH,Kim JH,Oh BH,Hong CH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Dizzy patients with both psychological and physical symptoms tend to have high levels of disability and are at risk of remaining symptomatic and disabled. The objective of this study was to develop a prediction model for the presence of anxiety and/or depression in older dizzy patients in primary care. METH...

journal_title：Journal of geriatric psychiatry and neurology

authors： Maarsingh OR,Dros J,van der Windt DA,ter Riet G,Schellevis FG,van Weert HC,van der Horst HE

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Older adults with severe psychiatric illness are often treated at community mental health centers (CMHCs) and these individuals commonly have numerous risk factors for cognitive impairment (CI). Brief cognitive screening instruments are frequently used to evaluate cognitive functioning in CMHCs, but the vali...

journal_title：Journal of geriatric psychiatry and neurology

authors： Mackin RS,Ayalon L,Feliciano L,Areán PA

更新日期：2010-06-01 00:00:00

abstract：:The main objectives of this study were to examine the relationship between cognitive deficits, as measured by the Mini-Mental Status Examination (MMSE), and decision-making capacity and to determine whether the sensitivity and specificity of the MMSE varied based upon the patient population assessed. Using a sample si...

journal_title：Journal of geriatric psychiatry and neurology

authors： Pachet A,Astner K,Brown L

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To identify clinical manifestations and neuropsychological effects of Alzheimer disease (AD) in apolipoprotein (ApoE) e4 carriers and to investigate the relationships between ApoE HhaI polymorphism and apolipoprotein C1 (APOC1) HpaI polymorphism in Taiwanese patients with AD. PARTICIPANTS AND METHODS:A total...

journal_title：Journal of geriatric psychiatry and neurology

authors： Chuang WL,Hsieh YC,Wang CY,Kuo HC,Huang CC

更新日期：2010-03-01 00:00:00

abstract：:The objective of the study was to evaluate incident cases of Alzheimer disease (AD) and mild cognitive impairment (MCI) in an elderly community cohort in a major city of southern Brazil and to determine the variables associated with the development of cognitive dysfunction. Data were drawn from a cohort to investigate...

journal_title：Journal of geriatric psychiatry and neurology

authors： Chaves ML,Camozzato AL,Godinho C,Piazenski I,Kaye J

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The brain-at-risk stage is the earliest phase of the vascular cognitive impairment continuum and includes individuals with vascular risk factors (VRF). However, there is still no clear definition of this concept. The aim of the study is to characterize the neuropsychological profile of elderly individuals by...

journal_title：Journal of geriatric psychiatry and neurology

authors： Wiederkehr S,Laurin D,Simard M,Verreault R,Lindsay J

更新日期：2009-09-01 00:00:00

abstract：:Apolipoprotein E gene alleles have been linked to various cardiovascular and neurodegenerative disorders. There have been conflicting reports of associations between Apolipoprotein E alleles and Parkinson disease and Parkinson disease dementia. To investigate the role of Apolipoprotein E alleles in Parkinson disease a...

journal_title：Journal of geriatric psychiatry and neurology

authors： Kurz MW,Dekomien G,Nilsen OB,Larsen JP,Aarsland D,Alves G

更新日期：2009-09-01 00:00:00

abstract：:The association between cytokines (IL-1 beta, sIL-4R, IL-6, IL-8, IL-10, IL-12, TNF-alpha) and subcortical white matter lesions, cortical atrophy and lacunar infarctions of the aging brain was investigated among 268 elderly community participants. Single pro- and anti-inflammatory cytokines were neither associated wit...

journal_title：Journal of geriatric psychiatry and neurology

authors： Baune BT,Ponath G,Rothermundt M,Roesler A,Berger K

更新日期：2009-03-01 00:00:00

abstract：:We investigated the relation between parental education and dementia in the United States. Participants in the Aging, Demographics, and Memory Study were included, with information regarding parental education obtained from the Health and Retirement Study. The odds of dementia in elderly Americans whose mothers had le...

journal_title：Journal of geriatric psychiatry and neurology

authors： Rogers MA,Plassman BL,Kabeto M,Fisher GG,McArdle JJ,Llewellyn DJ,Potter GG,Langa KM

更新日期：2009-03-01 00:00:00

abstract：:We review the literature for evidence of posttraumatic stress disorder that emerges in older adulthood yet is related to earlier life events. Minimum standards necessary to establish the phenomenon are proposed and applied to existing group and case studies. Our findings suggest that the best evidence for this rests w...

journal_title：Journal of geriatric psychiatry and neurology

authors： Hiskey S,Luckie M,Davies S,Brewin CR

更新日期：2008-12-01 00:00:00

abstract：:The purpose of this study was to examine the association between dependence in activities of daily living (ADL) and instrumental ADL (IADL) and major depression among 415 community-dwelling primary care patients age 65+ with heart failure and significant ADL or IADL dependence. Main findings include (1) a progressive ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Friedman B,Lyness JM,Delavan RL,Chunyu Li,Barker WH

更新日期：2008-06-01 00:00:00

abstract：:The purpose of this study was to evaluate whether distinct subtypes of depression could be identified in patients with Alzheimer's disease and, if so, to evaluate the patients in these subgroups. Ratings on the Cornell Scale for Depression in Dementia (CSDD) of 306 patients with Alzheimer's disease, 129 of whom were S...

journal_title：Journal of geriatric psychiatry and neurology

authors： Ownby RL,Acevedo A,Harwood DG,Barker WW,Duara R

更新日期：2008-03-01 00:00:00

abstract：:There have been increasing efforts to develop cognitive interventions to ameliorate cognitive problems experienced by older adults. In healthy elderly populations, cognitive training has centered on the enhancement of memory and speed of processing, with the goal of maximizing current function and reducing the risk of...

journal_title：Journal of geriatric psychiatry and neurology

authors： Acevedo A,Loewenstein DA

更新日期：2007-12-01 00:00:00

abstract：:Clinical profiles of delirium in 717 older people with and without dementia age 75 years and older in 4 different types of care were studied. Delirium and dementia were diagnosed according to DSM-IV criteria. Delirious demented participants (n = 135) had more often had previous delirium episodes and were more often be...

journal_title：Journal of geriatric psychiatry and neurology

authors： Edlund A,Lundström M,Sandberg O,Bucht G,Brännström B,Gustafson Y

更新日期：2007-09-01 00:00:00

abstract：:Little is known about the prevalence and correlates of psychotropic drug use in community-dwelling elders with dementia. Baseline data from 285 community-dwelling elders with a research classification of dementia enrolled in the observational Memory and Medical Care Study were analyzed. Of these, 33.3% with a research...

journal_title：Journal of geriatric psychiatry and neurology

authors： Chan DC,Kasper JD,Black BS,Rabins PV

更新日期：2007-06-01 00:00:00

abstract：:The prevalence of neuropsychiatric symptoms and the influence of predictive factors in cognitively impaired nursing home patients were reviewed. Articles were identified by means of a MEDLINE and PsychInfo literature search. Neuropsychiatric symptoms were present in more than 80% of the cognitively impaired patients. ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Zuidema S,Koopmans R,Verhey F

更新日期：2007-03-01 00:00:00

abstract：:The authors compared the accuracy of Addenbrooke's Cognitive Examination Clock Drawing Test scoring method with 8 standard Clock Drawing Test scoring methods in a Spanish speaking population of low educational level. A clinical group composed of 70 patients affected by dementia and 25 patients with memory complaints w...

journal_title：Journal of geriatric psychiatry and neurology

authors： García-Caballero A,Recimil MJ,García-Lado I,Gayoso P,Cadarso-Suárez C,González-Hermida J,Area R,Lamas S

更新日期：2006-12-01 00:00:00

abstract：:Structural neuroimaging is a routine component of the diagnostic evaluation of dementia that is used to rule out potential causes of mental impairment, whereas functional imaging can differentiate different forms of dementia. Neuroimaging also offers promise as a surrogate marker for clinical trials, and new technolog...

journal_title：Journal of geriatric psychiatry and neurology

authors： Small GW

更新日期：2006-09-01 00:00:00

abstract：:The objective of this study was to examine the prevalence and clinical correlates of poststroke cognitive impairment in Chinese stroke patients in Hong Kong. One hundred seventy-nine stroke patients were interviewed by a psychiatrist 3 months after their stroke. Cognitive impairment was determined according to the Min...

journal_title：Journal of geriatric psychiatry and neurology

authors： Tang WK,Chan SS,Chiu HF,Ungvari GS,Wong KS,Kwok TC,Mok V,Wong KT,Richards PS,Ahuja AT

更新日期：2006-06-01 00:00:00

abstract：:The objective was to compare brain perfusion image using 3-dimensional stereotactic surface projection analysis of N-isopropyl-p-123I iodoamphetamine single photon emission computed tomography between Parkinson's disease patients with a high frontal assessment battery score and those with a low frontal assessment batt...

journal_title：Journal of geriatric psychiatry and neurology

authors： Matsui H,Udaka F,Miyoshi T,Hara N,Tamura A,Oda M,Kubori T,Nishinaka K,Kameyama M

更新日期：2006-03-01 00:00:00

abstract：:Nondemented co-twins of twins who were diagnosed as demented were compared to randomly selected members of normal control twin pairs in which both members of the pair were nondemented. Nondemented co-twins included 23 monozygotic and 62 dizygotic twins; there were 27 normal control twins. Both monozygotic and dizygoti...

journal_title：Journal of geriatric psychiatry and neurology

authors： Gatz M,Fiske A,Reynolds CA,Johansson B,Fratiglioni L,Pedersen NL

更新日期：2005-12-01 00:00:00

abstract：:The objective was to evaluate the course and severity of dementia-related symptoms and their relationship to caregivers' subjective burden and depression over time. Forty-five patients with dementia and their caregivers were followed over a period of 2 years. Patients' cognition, function, and behavioral/psychological...

journal_title：Journal of geriatric psychiatry and neurology

authors： Berger G,Bernhardt T,Weimer E,Peters J,Kratzsch T,Frolich L

更新日期：2005-09-01 00:00:00

abstract：:Several studies have evaluated executive function in depressed patients, and the results vary from significant impairment relative to controls to virtually intact performances. To better comprehend executive impairment in elderly patients with major unipolar depression, the performance of 21 elderly depressed patients...

journal_title：Journal of geriatric psychiatry and neurology

authors： Baudic S,Tzortzis C,Barba GD,Traykov L

更新日期：2004-12-01 00:00:00

abstract：:This article reviews the cholinergic changes in Parkinson's disease and dementia (PDD) and dementia with Lewy bodies (DLB), their potential clinical implications, and the available evidence for cholinesterase inhibitors in the treatment of PDD and DLB. Marked neuronal loss of cholinergic nuclei, reduced cholinergic ma...

journal_title：Journal of geriatric psychiatry and neurology

authors： Aarsland D,Mosimann UP,McKeith IG

更新日期：2004-09-01 00:00:00

abstract：:Depression is commonly found in older adult patients and is often associated with handicaps. The authors administered the Comprehensive Geriatric Assessment (CGA), including basic activities of daily living (BADL), instrumental activities of daily living (IADL), Mini-Mental State Examination (MMSE), Geriatric Depressi...

journal_title：Journal of geriatric psychiatry and neurology

authors： Onishi J,Umegaki H,Suzuki Y,Uemura K,Kuzuya M,Iguchi A

更新日期：2004-06-01 00:00:00

abstract：:Although many older adults with serious psychiatric illnesses share common concerns, such as medical comorbidity, personal loss, greater propensity for adverse medication effects, and greater dependence on others for basic needs such as transportation, individualized treatment needs must be differentiated by underlyin...

journal_title：Journal of geriatric psychiatry and neurology

authors： Sajatovic M,Friedman SH,Sabharwal J,Bingham CR

更新日期：2004-03-01 00:00:00

abstract：:This article proposes an initial nomenclature and systematic approach for the nonpharmacologic understanding and treatment of psychotic symptoms in dementia. An analysis of delusions and hallucinations must examine alternative etiologies, including misdiagnosis and misunderstanding, the misinterpretation of reality be...

journal_title：Journal of geriatric psychiatry and neurology

authors： Cohen-Mansfield J

更新日期：2003-12-01 00:00:00

abstract：:Trauma-related nightmares in posttraumatic stress disorder (PTSD) rarely respond to pharmacologic treatment. Neurobiologic data suggest that enhanced brain responsiveness to adrenergic stimulation may contribute to the pathophysiology of trauma-related nightmares in PTSD. Nine older men with chronic PTSD secondary to ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Peskind ER,Bonner LT,Hoff DJ,Raskind MA

更新日期：2003-09-01 00:00:00

abstract：:The number of patients in nursing homes with severe cognitive impairment (SCI) is growing. The authors compared the characteristics and 6-month outcomes of a sample of nursing home residents with SCI to those of other residents. This cross-sectional and 6-month follow-up study used data from pooled 1990 and 1993 cohor...

journal_title：Journal of geriatric psychiatry and neurology

authors： Buttar AB,Mhyre J,Fries BE,Blaum CS

更新日期：2003-06-01 00:00:00

abstract：:Delirium is a neuropsychiatric syndrome characterized by impairment of consciousness, changes in cognition, or perceptual disturbances. In addition, delirium is often accompanied by delusions, hallucinations, and agitation. In this study, 12 older patients with delirium were treated for neuropsychiatric symptoms with ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Kim KY,Bader GM,Kotlyar V,Gropper D

更新日期：2003-03-01 00:00:00

abstract：:Th determine if teaching caregivers behavior management techniques (BMTs) reduces long-term psychotropic use in Alzheimer's disease (AD) patients, we examined 12-month follow-up data from a 4-month randomized study comparing placebo, BMTs, trazodone, and haloperidol for the treatment of agitated behaviors in persons w...

journal_title：Journal of geriatric psychiatry and neurology

authors： Weiner MF,Tractenberg RE,Sano M,Logsdon R,Teri L,Galasko D,Gamst A,Thomas R,Thal LJ

更新日期：2002-07-01 00:00:00

abstract：:Psychotic symptoms occurring in Alzheimer's disease (AD + psychosis, AD + P) are a marker for a more rapidly deteriorating phenotype. We have developed a polygenic model of AD + P risk, conditioned on the presence of AD. Whether risk genes for AD itself contribute to AD + P risk is not established, although our model ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Sweet RA,Kamboh MI,Wisniewski SR,Lopez OL,Klunk WE,Kaufer DI,DeKosky ST

更新日期：2002-04-01 00:00:00

abstract：:In the current study of 1062 Alzheimer's disease (AD) patients, we employed receiver operating characteristic curve analysis to identify characteristics of patients at increased risk for rapid cognitive decline. The patients are participants at one of the nine Alzheimer's Disease Research Centers of California. Rapid ...

journal_title：Journal of geriatric psychiatry and neurology

authors： O'Hara R,Thompson JM,Kraemer HC,Fenn C,Taylor JL,Ross L,Yesavage JA,Bailey AM,Tinklenberg JR

更新日期：2002-01-01 00:00:00

abstract：:This report describes the operation of a telepsychiatry consultation service provided from an academic medical center to a skilled nursing facility in a rural setting. Seventy-one consultations via low-cost ISDN videoconferencing equipment were provided over the 2-year period to 40 patients. The average duration of th...

journal_title：Journal of geriatric psychiatry and neurology

authors： Johnston D,Jones BN 3rd

更新日期：2001-07-01 00:00:00

abstract：:Normal aging of the brain affects the basal ganglia-thalamocortical circuits. These circuits are implicated in several neuropsychiatric disorders. Normal aging may therefore influence the symptomatology of psychiatric disorders in the elderly. We investigated motivational behavior that is associated with the function ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Lampe IK,Kahn RS,Heeren TJ

更新日期：2001-04-01 00:00:00

abstract：:Research subjects face uncertainties, risks, burdens, and indignities, and research protocol requirements inhibit the physician's ability to make individualized treatment decisions. To address these problems, investigators and Institutional Review Boards (IRBs) should justify research risks using informed consent and ...

journal_title：Journal of geriatric psychiatry and neurology

authors： Karlawish JH,Casarett D

更新日期：2001-01-01 00:00:00